Are Albendazole and Ivermectin Premix safe for deworming?
Publish Time: 2024-10-30
Albendazole and ivermectin are both widely used drugs for deworming treatment, and they are usually effective against a variety of internal and external parasites. These two drugs are made into premix form and are usually used for animal deworming in animal husbandry.
1. Deworming effect of albendazole and ivermectin
Albendazole: Mainly used to treat a variety of internal parasitic infections (such as roundworms, hookworms, tapeworms, etc.). It inhibits the parasite's absorption of glucose, causing its energy exhaustion and death.
Ivermectin: Mainly used to treat internal and external parasites (such as mites, lice, nematodes, etc.). It increases the permeability of the parasite's postsynaptic membrane to chloride ions, causing parasite paralysis and death.
When used in combination, the two have a broad-spectrum deworming effect and can target a variety of parasites, so they are often used in combination in animal husbandry to expand the scope of deworming.
2. Safety of premix
Dosage control: Albendazole and ivermectin in premix must be used strictly according to the recommended dose. Excessive dose may cause toxic reactions, while insufficient dose may lead to poor deworming effect. Therefore, it is critical to ensure that the premix is used correctly according to the product instructions or veterinary guidance.
Target of use: Premix is usually used for livestock such as pigs, cattle, sheep and other animals. Different types of animals have different tolerance to drugs. When using, it is necessary to follow relevant regulations to avoid using it on inappropriate animal species.
Withdrawal period: To ensure food safety, after using Albendazole And Ivermectin Premix, the prescribed withdrawal period (i.e., the time from the last dose to the time when the animal can be slaughtered or its products can enter the market) must be observed. This is to ensure that the drug residues can be fully metabolized in the animal body to avoid affecting human health.
3. Potential side effects
Side effects in animals: Albendazole and ivermectin are generally safe at the recommended dose, but side effects may occur in cases of overdose or when the animal is sensitive to the drug. For example:
Ivermectin may cause neurological symptoms (such as ataxia, respiratory depression, etc.) at high doses, especially in animal breeds that are sensitive to the drug (such as sheepdogs).
Albendazole may cause bone marrow suppression or liver dysfunction at very high doses, but is generally safe at recommended doses.
Potential risks to humans: Although albendazole and ivermectin are mainly used in animals, humans may suffer health problems if they ingest meat or other animal products containing residues of these drugs. Therefore, strict adherence to withdrawal periods and dosage regulations is crucial.
Albendazole And Ivermectin Premix can be used safely and effectively for animal deworming, but only if it is used strictly in accordance with the recommended dose and in compliance with withdrawal periods and relevant regulations. As long as these guidelines are followed, they can effectively control and prevent a variety of parasitic infections and protect animal health and production benefits.
